|Application ||WB, FC, E|
|Calculated MW||29751 Da|
|Antigen Region||206-233 aa|
|Other Names||2-aminoethanethiol dioxygenase, Cysteamine dioxygenase, ADO, C10orf22|
|Target/Specificity||This ADO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-233 amino acids from the C-terminal region of human ADO.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ADO Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 18.104.22.168). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM].
Dominy, J.E. Jr., et al. J. Biol. Chem. 282(35):25189-25198(2007)
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