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RARS Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP11091b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP11091b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
RARS Antibody (C-term) - Product info | |
| Application | WB, IHC, IF, FC
|
| Primary Accession | P54136 |
| Other Accession | NP_002878.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 75379 Da |
RARS Antibody (C-term) - Additional info | |
| Gene ID 5917 | |
| Other Names RARS; Arginine--tRNA ligase, cytoplasmic; Arginyl-tRNA synthetase | |
| Target/Specificity This RARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 612-642 amino acids from the C-terminal region of human RARS. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 IF~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RARS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RARS Antibody (C-term) - Protein Information | |
| Name RARS | |
| Function Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1 | |
| Cellular Location Cytoplasm. | |
RARS Antibody (C-term) - Related products
AP11091b: RARS Antibody (C-term)
AP7988c: RARS Antibody (Center)
DC00252: Human RARS cDNA Clone
LY13757a: RARS Over-expression Lysate
RARS Antibody (C-term) - Application data
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RARS Antibody (C-term) (Cat. #AP11091b) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RARS antibody detected the RARS protein (arrow).
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RARS Antibody (C-term) (Cat. #AP11091b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RARS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Confocal immunofluorescent analysis of RARS Antibody (C-term)(Cat#AP11091b) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
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RARS Antibody (C-term) (Cat. #AP11091b) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
RARS Antibody (C-term) - Research Areas
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BACKGROUND
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq].
REFERENCES
Bottoni, A., et al. J. Cell. Physiol. 212(2):293-297(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Ling, C., et al. J. Biol. Chem. 280(41):34755-34763(2005) Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003) Kaminska, M., et al. Biochemistry 40(47):14309-14316(2001)