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GAL Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - GAL Antibody (Center) AP11103c
    Confocal immunofluorescent analysis of GAL Antibody (Center)(Cat#AP11103c) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
    detail
  • WB - GAL Antibody (Center) AP11103c
    GAL Antibody (Center) (Cat. #AP11103c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GAL antibody detected the GAL protein (arrow).
    detail
  • IHC-P - GAL Antibody (Center) AP11103c
    GAL Antibody (Center) (Cat. #AP11103c)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GAL Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P22466
Other Accession NP_057057.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 13302 Da
Antigen Region 48-79 aa
Additional Information
Gene ID 51083
Other Names Galanin peptides, Galanin, Galanin message-associated peptide, GMAP, GAL, GAL1, GALN, GLNN
Target/Specificity This GAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-79 amino acids from the Central region of human GAL.
Dilution IF~~1:10~50
WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGAL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAL
Synonyms GAL1, GALN, GLNN
Function Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Cellular Location Secreted
Research Areas
Citations (0)
citation

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Background

Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Unschuld, P.G., et al. Neuropsychopharmacology 35(7):1583-1592(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 182.50
$ 70.00
Cat# AP11103c
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