|Application ||WB, IHC-P, IF, E|
|Calculated MW||13302 Da|
|Antigen Region||48-79 aa|
|Other Names||Galanin peptides, Galanin, Galanin message-associated peptide, GMAP, GAL, GAL1, GALN, GLNN|
|Target/Specificity||This GAL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-79 amino acids from the Central region of human GAL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GAL1, GALN, GLNN|
|Function||Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.|
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Provided below are standard protocols that you may find useful for product applications.
Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Unschuld, P.G., et al. Neuropsychopharmacology 35(7):1583-1592(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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