C1QL3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q5VWW1 |
Other Accession | Q9ESN4, NP_001010908.1 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26719 Da |
Antigen Region | 22-50 aa |
Gene ID | 389941 |
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Other Names | Complement C1q-like protein 3, C1q and tumor necrosis factor-related protein 13, C1q/TNF-related protein 13, C1QL3, CTRP13 |
Target/Specificity | This C1QL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human C1QL3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | C1QL3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | C1QL3 |
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Synonyms | CTRP13 |
Function | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production (By similarity). |
Cellular Location | Secreted. |
Tissue Location | Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential).
References
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Koide, T., et al. J. Biol. Chem. 275(36):27957-27963(2000)
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