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MYO19 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | Q96H55 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 109135 Da |
| Antigen Region | 554-582 aa |
| Gene ID | 80179 |
|---|---|
| Other Names | Unconventional myosin-XIX, Myosin head domain-containing protein 1, MYO19, MYOHD1 |
| Target/Specificity | This MYO19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 554-582 amino acids from the Central region of human MYO19. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MYO19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYO19 {ECO:0000303|PubMed:19932026, ECO:0000312|HGNC:HGNC:26234} |
|---|---|
| Function | Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed:25447992). May be involved in mitochondrial transport or positioning (PubMed:23568824). |
| Cellular Location | Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton |
| Tissue Location | Widely expressed in multiple tissues and cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity).
References
Quintero, O.A., et al. Curr. Biol. 19(23):2008-2013(2009)
Odronitz, F., et al. Genome Biol. 8 (9), R196 (2007) :
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