|Application ||WB, FC, E|
|Calculated MW||109135 Da|
|Antigen Region||554-582 aa|
|Other Names||Unconventional myosin-XIX, Myosin head domain-containing protein 1, MYO19, MYOHD1|
|Target/Specificity||This MYO19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 554-582 amino acids from the Central region of human MYO19.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYO19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.|
|Cellular Location||Cytoplasm, cytoskeleton. Mitochondrion outer membrane. Note=Probably associated with the outer membrane via its N-terminal mitochondrial targeting region|
|Tissue Location||Widely expressed in multiple tissues and cell lines.|
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Provided below are standard protocols that you may find useful for product applications.
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity).
Quintero, O.A., et al. Curr. Biol. 19(23):2008-2013(2009)
Odronitz, F., et al. Genome Biol. 8 (9), R196 (2007) :
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