|Application ||WB, FC, E|
|Calculated MW||51106 Da|
|Antigen Region||86-114 aa|
|Other Names||Probable G-protein coupled receptor 142, G-protein coupled receptor PGR2, GPR142, PGR2|
|Target/Specificity||This GPR142 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the N-terminal region of human GPR142.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR142 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Exclusively expressed in the central nervous system, most abundantly in the ventrolateral region of caudate putamen, the habenular nucleus, the zona incerta, and the medial mammillary nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).
Matsuo, A., et al. Biochem. Biophys. Res. Commun. 331(1):363-369(2005)
Fredriksson, R., et al. FEBS Lett. 554(3):381-388(2003)
Vassilatis, D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100(8):4903-4908(2003)
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