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ZNF322B Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ZNF322B Antibody (C-term) AP11403a
    ZNF322B Antibody (C-term) (Cat. #AP11403a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ZNF322B antibody detected the ZNF322B protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6U7Q0
Other Accession Q4R7X8, Q5SYY0, NP_945356.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46941 Da
Antigen Region 326-354 aa
Additional Information
Gene ID 79692
Other Names Zinc finger protein 322, Zinc finger protein 322A, Zinc finger protein 388, Zinc finger protein 489, ZNF322, ZNF322A, ZNF388, ZNF489
Target/Specificity This ZNF322B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-354 amino acids from the C-terminal region of human ZNF322B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZNF322B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF322
Synonyms ZNF322A, ZNF388, ZNF489
Function Transcriptional activator (PubMed:15555580). Important for maintenance of pluripotency in embryonic stem cells (By similarity). Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity). Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity). Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Mainly found in the nucleus
Tissue Location Ubiquitous. Highly expressed in heart and skeletal muscle.
Citations (0)
citation

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Background

May be involved in transcriptional regulation (By similarity).

References

Humphray, S.J., et al. Nature 429(6990):369-374(2004)

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$ 365.00
$ 140.00
Cat# AP11403a
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