GDPD1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q8N9F7 |
Other Accession | NP_001159465.1, NP_001159466.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36167 Da |
Antigen Region | 18-46 aa |
Gene ID | 284161 |
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Other Names | Glycerophosphodiester phosphodiesterase domain-containing protein 1, 31--, Glycerophosphodiester phosphodiesterase 4, GDPD1, GDE4 |
Target/Specificity | This GDPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human GDPD1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | GDPD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GDPD1 (HGNC:20883) |
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Function | Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (PubMed:27637550, PubMed:25596343). Shows a preference for 1-O-alkyl- sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC) (PubMed:27637550, PubMed:25596343). May be involved in bioactive N-acylethanolamine biosynthesis from both N-acyl-lysoplasmenylethanolamin (N-acyl- lysoPlsEt) and N-acyl-lysophosphatidylethanolamin (N-acyl-lysoPE) (PubMed:27637550, PubMed:25596343). In addition, hydrolyzes glycerophospho-N-acylethanolamine to N-acylethanolamine (PubMed:27637550). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (By similarity). |
Cellular Location | Cytoplasm. Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Concentrated at the perinuclear region and the cell periphery (PubMed:18991142) |
Tissue Location | Widely expressed with high expression level in testis. |
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