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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   STRA8 Antibody (C-term)   

STRA8 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - STRA8 Antibody (C-term) AP11436b
    STRA8 Antibody (C-term) (Cat. #AP11436b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the STRA8 antibody detected the STRA8 protein (arrow).
  • IHC-P - STRA8 Antibody (C-term) AP11436b
    STRA8 Antibody (C-term) (Cat. #AP11436b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STRA8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - STRA8 Antibody (C-term) AP11436b
    Confocal immunofluorescent analysis of STRA8 Antibody (C-term)(Cat#AP11436b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z7C7
Other Accession NP_872295.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36908 Da
Antigen Region 286-315 aa
Additional Information
Gene ID 346673
Other Names Stimulated by retinoic acid gene 8 protein homolog, STRA8 {ECO:0000312|EMBL:AAP471631}
Target/Specificity This STRA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human STRA8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTRA8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STRA8 {ECO:0000312|EMBL:AAP47163.1}
Function Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P70278}.
Tissue Location Expressed specifically in testis.
Research Areas
Citations (0)

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This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.


Le Bouffant, R., et al. Hum. Reprod. 25(10):2579-2590(2010)
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Chen, B., et al. Asian J. Androl. 11(5):557-565(2009)
Houmard, B., et al. Biol. Reprod. 81(2):438-443(2009)
Stouffs, K., et al. Verh. K. Acad. Geneeskd. Belg. 71(3):115-139(2009)

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Cat# AP11436b
(40 western blots)
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