|Application ||WB, E|
|Calculated MW||47030 Da|
|Antigen Region||179-208 aa|
|Other Names||Carboxypeptidase A2, CPA2|
|Target/Specificity||This CPA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-208 amino acids from the Central region of human CPA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein.
Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Cerda-Costa, N., et al. Biochemistry 48(44):10582-10590(2009)
Dantas, G., et al. J. Mol. Biol. 366(4):1209-1221(2007)
Fu, G.K., et al. Genomics 84(1):205-210(2004)
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