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XKR4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q5GH76 |
| Other Accession | Q5GH59, Q5GH67, NP_443130.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 71501 Da |
| Antigen Region | 570-598 aa |
| Gene ID | 114786 |
|---|---|
| Other Names | XK-related protein 4, XKR4, KIAA1889, XRG4 |
| Target/Specificity | This XKR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-598 amino acids from the C-terminal region of human XKR4. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | XKR4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | XKR4 {ECO:0000303|PubMed:25231987, ECO:0000312|HGNC:HGNC:29394} |
|---|---|
| Function | [XK-related protein 4, processed form]: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:25231987, PubMed:33725486). Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (PubMed:25231987, PubMed:33725486). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q5GH67}; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of the protein remains unknown.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lavedan, C., et al. Mol. Psychiatry 14(8):804-819(2009)
Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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