|Application ||WB, E|
|Calculated MW||52319 Da|
|Antigen Region||466-493 aa|
|Other Names||Monocarboxylate transporter 3, MCT 3, Solute carrier family 16 member 8, SLC16A8, MCT3|
|Target/Specificity||This SLC16A8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-493 amino acids from the C-terminal region of human SLC16A8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC16A8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Retinal pigment epithelium.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM].
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Wilson, M.C., et al. J. Biol. Chem. 280(29):27213-27221(2005)
Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)
Philp, N.J., et al. Invest. Ophthalmol. Vis. Sci. 44(4):1716-1721(2003)
Dunham, I., et al. Nature 402(6761):489-495(1999)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.