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OTX2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - OTX2 Antibody (C-term) AP11681b
    OTX2 Antibody (C-term) (Cat.# AP11681b) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the OTX2 antibody detected the OTX2 protein (arrow).
  • IHC-P - OTX2 Antibody (C-term) AP11681b
    OTX2 Antibody (C-term) (Cat. #AP11681b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32243
Other Accession P80206, Q91981, Q6DKN2, Q91813, NP_068374.1, NP_758840.1
Reactivity Human
Predicted Zebrafish, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31636 Da
Antigen Region 261-289 aa
Additional Information
Gene ID 5015
Other Names Homeobox protein OTX2, Orthodenticle homolog 2, OTX2
Target/Specificity This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOTX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OTX2
Function Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
Cellular Location Nucleus.
Tissue Location Expressed in brain.
Research Areas
Citations (0)

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This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)
Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)
Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :
Ashkenazi-Hoffnung, L., et al. Hum. Genet. 127(6):721-729(2010)

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Cat# AP11681b
(40 western blots)
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