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PURA Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - PURA Antibody (C-term) AP11789b
    PURA Antibody (C-term) (Cat. #AP11789b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PURA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • WB - PURA Antibody (C-term) AP11789b
    PURA Antibody (C-term) (Cat. #AP11789b) western blot analysis in A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the PURA antibody detected the PURA protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q00577
Other Accession P42669, NP_005850.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34911 Da
Antigen Region 259-287 aa
Additional Information
Gene ID 5813
Other Names Transcriptional activator protein Pur-alpha, Purine-rich single-stranded DNA-binding protein alpha, PURA, PUR1
Target/Specificity This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.
Dilution IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPURA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PUR1
Function This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.
Cellular Location Nucleus.
Citations (0)

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This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.


Inoue, T., et al. Prostate 69(8):861-873(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Kaminski, R., et al. Cancer Biol. Ther. 7(12):1926-1935(2008)
Darbinian, N., et al. J. Alzheimers Dis. 15(1):71-82(2008)
Wang, L.G., et al. Cancer Res. 68(8):2678-2688(2008)

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Cat# AP11789b
(40 western blots)
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