- CITATIONS: 1
|Application ||WB, IHC-P, IF, FC, E|
|Other Accession||Q01721, NP_002039|
|Calculated MW||35693 Da|
|Antigen Region||95-127 aa|
|Other Names||Growth arrest-specific protein 1, GAS-1, GAS1|
|Target/Specificity||This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-127 amino acids from the N-terminal region of human GAS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAS1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
Provided below are standard protocols that you may find useful for product applications.
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
Ribeiro, L.A., et al. Am. J. Med. Genet. A 152A (7), 1688-1694 (2010) : Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) : Rittie, L., et al. Aging Cell 8(6):738-751(2009) Zhao, L., et al. J. Biol. Chem. 284(39):26273-26285(2009) Dominguez-Monzon, G., et al. Int. J. Dev. Neurosci. 27(4):305-313(2009)
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