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PRSS3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRSS3 Antibody (Center) AP11927c
    All lanes : Anti-PRSS3 Antibody (Center) at 1:1000 dilution Lane 1: MDA-MB-231 whole cell lysate Lane 2: human pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - PRSS3 Antibody (Center) AP11927c
    PRSS3 Antibody (Center) (Cat. #AP11927c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRSS3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PRSS3 Antibody (Center) AP11927c
    PRSS3 Antibody (Center) (Cat. #AP11927c) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35030
Other Accession NP_002762.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32529 Da
Antigen Region 136-163 aa
Additional Information
Gene ID 5646
Other Names Trypsin-3, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV, PRSS3, PRSS4, TRY3, TRY4
Target/Specificity This PRSS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the Central region of human PRSS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRSS3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS3
Synonyms PRSS4, TRY3, TRY4
Function Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
Cellular Location Secreted.
Tissue Location Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts
Research Areas
Citations (0)

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This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.


Jiang, G., et al. Gut 59(11):1535-1544(2010)
Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)
Salameh, M.A., et al. J. Biol. Chem. 285(3):1939-1949(2010)
Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010) :
Koistinen, H., et al. Neuroscience 160(1):97-102(2009)

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$ 295.00
$ 99.00
Cat# AP11927c
(40 western blots)
Availability: In Stock
Bulk Size
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