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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   POSTN Antibody (C-term)   

POSTN Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - POSTN Antibody (C-term) AP11962b
    POSTN Antibody (C-term) (Cat. #AP11962b) western blot analysis in MCF-7(lane 1),A375(lane 2) cell line lysates (35ug/lane).This demonstrates the POSTN antibody detected the POSTN protein (arrow).
  • IHC-P - POSTN Antibody (C-term) AP11962b
    POSTN Antibody (C-term) (Cat. #AP11962b)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POSTN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - POSTN Antibody (C-term) AP11962b
    Confocal immunofluorescent analysis of POSTN Antibody (C-term)(Cat#AP11962b) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15063
Other Accession NP_006466
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 93314 Da
Antigen Region 687-716 aa
Additional Information
Gene ID 10631
Other Names Periostin, PN, Osteoblast-specific factor 2, OSF-2, POSTN, OSF2
Target/Specificity This POSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 687-716 amino acids from the C-terminal region of human POSTN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOSTN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms OSF2
Function Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity). Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
Cellular Location Golgi apparatus. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi.
Tissue Location Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor Overexpressed in breast cancers.
Research Areas
Citations ( 0 )


POSTN binds to heparin. It induces cell attachment and spreading and plays a role in cell adhesion and may play a role in extracellular matrix mineralization.


Zhu, M., et al. Gynecol. Oncol. 119(2):337-344(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Takada, M., et al. Biochem. Biophys. Res. Commun. 399(2):221-226(2010)
Sidhu, S.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14170-14175(2010)
Tischler, V., et al. BMC Cancer 10, 273 (2010) :

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$ 295.00
$ 99.00
Cat# AP11962b
(40 western blots)
Availability: In Stock
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