|Application ||WB, IHC-P, IF, E|
|Calculated MW||20437 Da|
|Antigen Region||39-66 aa|
|Other Names||Interleukin-17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, IL17B, IL20, NIRF, ZCYTO7|
|Target/Specificity||This IL17B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human IL17B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IL17B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||IL20, NIRF, ZCYTO7|
|Function||Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.|
|Tissue Location||Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
Koskinen, L.L., et al. Tissue Antigens 74(5):408-416(2009)
Wang, X., et al. Ann. Otol. Rhinol. Laryngol. 115(6):450-456(2006)
Ryan, A.W., et al. Tissue Antigens 65(2):150-155(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Moore, E.E., et al. Neuromuscul. Disord. 12(2):141-150(2002)
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