|Application ||WB, IF, IHC-P, FC, E|
|Calculated MW||47368 Da|
|Antigen Region||9-37 aa|
|Other Names||Carboxypeptidase B, Pancreas-specific protein, PASP, CPB1, CPB, PCPB|
|Target/Specificity||This CPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human CPB1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPB1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Pantoja-Uceda, D., et al. Biochemistry 47(27):7066-7078(2008)
Guimaraes, A.H., et al. Arterioscler. Thromb. Vasc. Biol. 27(10):2157-2162(2007)
Barbosa Pereira, P.J., et al. J. Mol. Biol. 321(3):537-547(2002)
Aloy, P., et al. Biol. Chem. 379(2):149-155(1998)
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