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TBCA Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBCA Antibody (Center) AP12024C
    Anti-TBCA Antibody (Center) at 1:1000 dilution + LNCaP whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 13 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - TBCA Antibody (Center) AP12024C
    TBCA Antibody (Center) (Cat. #AP12024c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TBCA antibody detected the TBCA protein (arrow).
  • IHC-P - TBCA Antibody (Center) AP12024C
    TBCA Antibody (Center) (Cat. #AP12024c)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TBCA Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75347
Other Accession NP_004598.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 12855 Da
Antigen Region 30-58 aa
Additional Information
Gene ID 6902
Other Names Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA
Target/Specificity This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the Central region of human TBCA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBCA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations (0)

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The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)
Nolasco, S., et al. FEBS Lett. 579(17):3515-3524(2005)
Guasch, A., et al. J. Mol. Biol. 318(4):1139-1149(2002)

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$ 295.00
$ 99.00
Cat# AP12024C
(40 western blots)
Availability: In Stock
Bulk Size
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