|Application ||WB, E|
|Calculated MW||26339 Da|
|Antigen Region||105-133 aa|
|Other Names||Homeobox protein Hox-A6, Homeobox protein Hox-1B, HOXA6, HOX1B|
|Target/Specificity||This HOXA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the Central region of human HOXA6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HOXA6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.|
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Provided below are standard protocols that you may find useful for product applications.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Dickson, G.J., et al. Exp. Hematol. 37(3):322-333(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Kosaki, K., et al. Teratology 65(2):50-62(2002)
Walters, J.R., et al. Gastroenterology 113(2):472-477(1997)
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