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DVL3 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP12030b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12030b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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DVL3 Antibody (C-term) - Product info | |
| Application | WB, IHC, IF
|
| Primary Accession | Q92997 |
| Other Accession | Q61062, NP_004414.3 |
| Reactivity | Human |
| Predicted | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 78055 Da |
DVL3 Antibody (C-term) - Additional info | |
| Gene ID 1857 | |
| Other Names DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; DSH homolog 3 | |
| Target/Specificity This DVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human DVL3. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 IF~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions DVL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
DVL3 Antibody (C-term) - Protein Information | |
| Name DVL3 | |
| Synonyms KIAA0208 | |
| Function May play a role in the signal transduction pathway mediated by multiple Wnt genes | |
| Cellular Location Cytoplasm (By similarity). | |
DVL3 Antibody (C-term) - Related products
AP12030b: DVL3 Antibody (C-term)
DC06396: Human DVL3 cDNA Clone
LY13797a: DVL3 Over-expression Lysate
DVL3 Antibody (C-term) - Application data
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DVL3 Antibody (C-term) (Cat. #AP12030b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DVL3 antibody detected the DVL3 protein (arrow).
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DVL3 Antibody (C-term) (Cat. #AP12030b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DVL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Confocal immunofluorescent analysis of DVL3 Antibody (C-term)(Cat#AP12030b) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
DVL3 Antibody (C-term) - Research Areas
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BACKGROUND
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
REFERENCES
Gnad, T., et al. Mol. Cancer 9, 31 (2010) : Bouteille, N., et al. Oncogene 28(28):2569-2580(2009) Fukukawa, C., et al. Oncogene 28(8):1110-1120(2009) Wei, Q., et al. Lung Cancer 62(2):181-192(2008) Lee, Y.N., et al. Cell. Signal. 20(2):443-452(2008)