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DVL3 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP12030b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP12030b-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
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  • Backgrounds

DVL3 Antibody (C-term) - Product info

ApplicationWB, IHC, IF
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ92997
Other AccessionQ61062, NP_004414.3
ReactivityHuman
PredictedMouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW78055 Da

DVL3 Antibody (C-term) - Additional info

Gene ID 1857
Other Names
DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; DSH homolog 3
Target/Specificity
This DVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human DVL3.
Dilution
WB~~1:100~500
IHC~~1:10~50
IF~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
DVL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

DVL3 Antibody (C-term) - Protein Information

Name DVL3
Synonyms KIAA0208
Function
May play a role in the signal transduction pathway mediated by multiple Wnt genes
Cellular Location
Cytoplasm (By similarity).

DVL3 Antibody (C-term) - Related products

AP12030b: DVL3 Antibody (C-term)

RI11640: DVL3 predesign siRNA

DC06396: Human DVL3 cDNA Clone

LY13797a: DVL3 Over-expression Lysate

AT1832a: DVL3 Antibody (monoclonal) (M04)

AJ1246a: Dsh-3 Antibody

DVL3 Antibody (C-term) - Application data

  • DVL3 Antibody (C-term) (Cat. #AP12030b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DVL3 antibody detected the DVL3 protein (arrow).

  • DVL3 Antibody (C-term) (Cat. #AP12030b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DVL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • Confocal immunofluorescent analysis of DVL3 Antibody (C-term)(Cat#AP12030b) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

DVL3 Antibody (C-term) - Research Areas

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BACKGROUND

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

REFERENCES

Gnad, T., et al. Mol. Cancer 9, 31 (2010) : Bouteille, N., et al. Oncogene 28(28):2569-2580(2009) Fukukawa, C., et al. Oncogene 28(8):1110-1120(2009) Wei, Q., et al. Lung Cancer 62(2):181-192(2008) Lee, Y.N., et al. Cell. Signal. 20(2):443-452(2008)