|Application ||WB, IHC-P, IF, E|
|Other Accession||Q61062, NP_004414.3|
|Calculated MW||78055 Da|
|Antigen Region||530-557 aa|
|Other Names||Segment polarity protein dishevelled homolog DVL-3, Dishevelled-3, DSH homolog 3, DVL3, KIAA0208|
|Target/Specificity||This DVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the C-terminal region of human DVL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DVL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the signal transduction pathway mediated by multiple Wnt genes.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
Gnad, T., et al. Mol. Cancer 9, 31 (2010) :
Bouteille, N., et al. Oncogene 28(28):2569-2580(2009)
Fukukawa, C., et al. Oncogene 28(8):1110-1120(2009)
Wei, Q., et al. Lung Cancer 62(2):181-192(2008)
Lee, Y.N., et al. Cell. Signal. 20(2):443-452(2008)
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