|Application ||WB, IHC-P, FC, E|
|Calculated MW||59084 Da|
|Antigen Region||495-524 aa|
|Other Names||Alpha-(1, 3)-fucosyltransferase 4, 241-, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase, FUT4, ELFT, FCT3A|
|Target/Specificity||This FUT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-524 amino acids from the C-terminal region of human FUT4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FUT4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
Yang, X.S., et al. J. Cell. Physiol. 225(2):612-619(2010) Trubiani, O., et al. J. Cell. Physiol. 225(1):123-131(2010) Pruszak, J., et al. Stem Cells 27(12):2928-2940(2009) Ogata, K., et al. Haematologica 94(8):1066-1074(2009) Read, T.A., et al. Cancer Cell 15(2):135-147(2009)
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