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SOX3 Antibody (Center P204)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | P41225 |
| Other Accession | P53784, Q6EJB7, P48433, Q5FWM3, P55863, Q2PG84, P53783, O00570, O57401, Q2Z1R2, Q6DGL6, NP_005625.2 |
| Reactivity | Human |
| Predicted | Zebrafish, Chicken, Mouse, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45210 Da |
| Antigen Region | 189-218 aa |
| Gene ID | 6658 |
|---|---|
| Other Names | Transcription factor SOX-3, SOX3 |
| Target/Specificity | This SOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the Central region of human SOX3. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SOX3 Antibody (Center P204) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOX3 |
|---|---|
| Function | Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). |
| Cellular Location | Nucleus. |
Research Areas
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$ 192.50
Cat# AP12071c
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