RBPMS2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q6ZRY4 |
Other Accession | Q9YGP5, Q9W6I1, NP_919248.1, Q6DH13 |
Reactivity | Mouse |
Predicted | Zebrafish, Chicken, Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 22497 Da |
Antigen Region | 113-141 aa |
Gene ID | 348093 |
---|---|
Other Names | RNA-binding protein with multiple splicing 2, RBPMS2 |
Target/Specificity | This RBPMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RBPMS2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RBPMS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RBPMS2 |
---|---|
Function | RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:25064856). Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity). Acts as a pre- mRNA alternative splicing regulator (By similarity). Mediates ACTN1 and FLNB alternative splicing (By similarity). Likely binds to mRNA tandem CAC trinucleotide or CA dinucleotide motifs (PubMed:24860013). |
Cellular Location | Cytoplasm. Nucleus Cytoplasm, Stress granule. Note=Localized to cytoplasmic stress granules after oxidative stress |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RBPMS2 contains one RRM (RNA recognition motif) domain. The exact function of RBPMS2 remains unknown.
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.