|Application ||WB, IHC-P, E|
|Other Accession||Q9YGP5, Q9W6I1, NP_919248.1|
|Calculated MW||22497 Da|
|Antigen Region||113-141 aa|
|Other Names||RNA-binding protein with multiple splicing 2, RBPMS2|
|Target/Specificity||This RBPMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RBPMS2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RBPMS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Contributes to the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system. Binds NOG mRNA. Mediates an increase of NOG mRNA levels, and thereby contributes to the negative regulation of the BMP signaling pathway. This promotes reversible dedifferentiation of smooth muscle cells and promotes smooth muscle cell proliferation.|
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Provided below are standard protocols that you may find useful for product applications.
RBPMS2 contains one RRM (RNA recognition motif) domain. The exact function of RBPMS2 remains unknown.
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
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