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SFTPA2B Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SFTPA2B Antibody (C-term) AP12232b
    SFTPA2B Antibody (C-term) (Cat. #AP12232b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SFTPA2B antibody detected the SFTPA2B protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8IWL1
Other Accession Q8IWL2, NP_001092138.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 26169 Da
Antigen Region 174-202 aa
Additional Information
Gene ID 729238
Other Names Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5, SFTPA2, COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B
Target/Specificity This SFTPA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the C-terminal region of human SFTPA2B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSFTPA2B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SFTPA2
Synonyms COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B
Function In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
Cellular Location Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film
Research Areas
Citations (0)
citation

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Background

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.

References

Silveyra, P., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L523-L534 (2010) :
Maitra, M., et al. J. Biol. Chem. 285(29):22103-22113(2010)
Wang, G., et al. J. Biol. Chem. 285(16):11998-12010(2010)
El Saleeby, C.M., et al. J. Pediatr. 156(3):409-414(2010)
Liu, J., et al. Tohoku J. Exp. Med. 221(1):35-42(2010)

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$ 365.00
$ 140.00
Cat# AP12232b
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