- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||112992 Da|
|Antigen Region||904-933 aa|
|Other Names||Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B|
|Target/Specificity||This GRIN3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the C-terminal region of human GRIN3B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GRIN3B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane|
Provided below are standard protocols that you may find useful for product applications.
GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :
Saus, E., et al. J Psychiatr Res (2010) In press :
Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)
Niemann, S., et al. Neurology 70(9):666-676(2008)
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