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>   home   >   Products   >   Primary Antibodies   >   DAZ2 Antibody (C-term)   

DAZ2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DAZ2 Antibody (C-term) AP12295b
    DAZ2 Antibody (C-term) (Cat. #AP12295b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DAZ2 antibody detected the DAZ2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13117
Other Accession Q86SG3, Q9NR90, Q9NQZ3, NP_001005785.1, NP_065096.1, NP_001005786.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 63111 Da
Antigen Region 518-546 aa
Additional Information
Gene ID 57055
Other Names Deleted in azoospermia protein 2, DAZ2
Target/Specificity This DAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DAZ2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDAZ2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DAZ2
Function RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis
Tissue Location Testis specific.
Citations (0)

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This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.


Kim, B., et al. Hum. Reprod. 24(6):1507-1515(2009)
Lardone, M.C., et al. Fertil. Steril. 88(5):1318-1326(2007)
A, Z.C., et al. Yi Chuan 28(9):1057-1060(2006)
Zhang, F., et al. Ann. Hum. Genet. 70 (PT 3), 304-313 (2006) :
Yang, Y., et al. Fertil. Steril. 85(4):1061-1063(2006)

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$ 295.00
$ 99.00
Cat# AP12295b
(40 western blots)
Availability: In Stock
Bulk Size
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