|Application ||WB, E|
|Calculated MW||28292 Da|
|Antigen Region||227-256 aa|
|Other Names||Aquaporin-5, AQP-5, AQP5|
|Target/Specificity||This AQP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the C-terminal region of human AQP5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AQP5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
Shen, Y., et al. Respir Physiol Neurobiol 171(3):212-217(2010)
Shen, L., et al. Biomed. Pharmacother. 64(5):313-318(2010)
Shankardas, J., et al. Mol. Vis. 16, 1538-1548 (2010) :
Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) :
Nejsum, L.N., et al. Proc. Natl. Acad. Sci. U.S.A. 99(1):511-516(2002)
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