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KCNJ8 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNJ8 Antibody (N-term) AP12302a
    KCNJ8 Antibody (N-term) (Cat. #AP12302a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNJ8 antibody detected the KCNJ8 protein (arrow).
  • IHC-P - KCNJ8 Antibody (N-term) AP12302a
    KCNJ8 Antibody (N-term) (Cat. #AP12302a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15842
Other Accession Q63664, P97794, NP_004973.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47968 Da
Antigen Region 4-33 aa
Additional Information
Gene ID 3764
Other Names ATP-sensitive inward rectifier potassium channel 8, Inward rectifier K(+) channel Kir61, Potassium channel, inwardly rectifying subfamily J member 8, uKATP-1, KCNJ8
Target/Specificity This KCNJ8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of human KCNJ8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNJ8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ8
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Predominantly detected in fetal and adult heart.
Research Areas
Citations (0)

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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. [provided by RefSeq].


Medeiros-Domingo, A., et al. Heart Rhythm 7(10):1466-1471(2010)
Ellis, J.A., et al. Physiol. Genomics 40(3):184-188(2010)
Shi, W., et al. J. Biol. Chem. 285(5):3021-3029(2010)
Winkler, M., et al. J. Biol. Chem. 284(11):6752-6762(2009)
Ploug, K.B., et al. Eur. J. Pharmacol. 601 (1-3), 43-49 (2008) :

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$ 295.00
$ 99.00
Cat# AP12302a
(40 western blots)
Availability: In Stock
Bulk Size
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