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COX7A2L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COX7A2L Antibody (Center) AP12338c
    Anti-COX7A2L Antibody (Center) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 13 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - COX7A2L Antibody (Center) AP12338c
    COX7A2L Antibody (Center) (Cat. #AP12338c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the COX7A2L antibody detected the COX7A2L protein (arrow).
  • WB - COX7A2L Antibody (Center) AP12338c
    COX7A2L Antibody (Center) (Cat. #AP12338c) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the COX7A2L antibody detected the COX7A2L protein (arrow).
  • IHC-P - COX7A2L Antibody (Center) AP12338c
    COX7A2L Antibody (Center) (Cat. #AP12338c)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COX7A2L Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14548
Other Accession NP_004709.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 12615 Da
Antigen Region 37-65 aa
Additional Information
Gene ID 9167
Other Names Cytochrome c oxidase subunit 7A-related protein, mitochondrial, COX7a-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1, COX7A2L, COX7AR, COX7RP
Target/Specificity This COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOX7A2L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COX7A2L
Synonyms COX7AR, COX7RP
Function Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity). Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).
Cellular Location Mitochondrion inner membrane.
Research Areas
Citations (0)

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Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.


Fornuskova, D., et al. Biochem. J. 428(3):363-374(2010)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Schmidt, T.R., et al. J. Mol. Evol. 57(2):222-228(2003)
Lee, N., et al. Am. J. Hum. Genet. 68(2):397-409(2001)

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$ 295.00
$ 99.00
Cat# AP12338c
(40 western blots)
Availability: In Stock
Bulk Size
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