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UGT2B15 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - UGT2B15 Antibody (Center) AP12375C
    UGT2B15 Antibody (Center) (Cat. #AP12375c) western blot analysis in NCI-H460(lane 1),HepG2(lane 2),ZR-75-1(lane 3) cell line lysates (35ug/lane).This demonstrates the UGT2B15 antibody detected the UGT2B15 protein (arrow).
  • IHC-P - UGT2B15 Antibody (Center) AP12375C
    UGT2B15 Antibody (Center) (Cat. #AP12375c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UGT2B15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - UGT2B15 Antibody (Center) AP12375C
    Confocal immunofluorescent analysis of UGT2B15 Antibody (Center) (Cat#AP12375c) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
  • FC - UGT2B15 Antibody (Center) AP12375C
    UGT2B15 Antibody (Center) (Cat. #AP12375c) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P54855
Other Accession NP_001067.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 61036 Da
Antigen Region 156-185 aa
Additional Information
Gene ID 7366
Other Names UDP-glucuronosyltransferase 2B15, UDPGT 2B15, HLUG4, UDP-glucuronosyltransferase 2B8, UDPGT 2B8, UDPGTh-3, UGT2B15, UGT2B8
Target/Specificity This UGT2B15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human UGT2B15.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUGT2B15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UGT2B15
Synonyms UGT2B8
Function UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
Cellular Location Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Expressed in many tissues. Present in liver, prostate and testis.
Research Areas
Citations ( 0 )


The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).


Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19(2):537-546(2010)
Sun, C., et al. Hum. Mutat. 31(1):99-107(2010)
Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
He, X., et al. Br J Clin Pharmacol 68(5):721-730(2009)
Holmes, M.V., et al. PLoS ONE 4 (12), E7960 (2009) :

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$ 295.00
$ 99.00
Cat# AP12375C
(40 western blots)
Availability: In Stock
Bulk Size
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