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CRYBA1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CRYBA1 Antibody (Center) AP12377c
    CRYBA1 Antibody (Center) (Cat. #AP12377c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the CRYBA1 antibody detected the CRYBA1 protein (arrow).
  • WB - CRYBA1 Antibody (Center) AP12377c
    CRYBA1 Antibody (Center) (Cat. #AP12377c) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CRYBA1 antibody detected the CRYBA1 protein (arrow).
  • IHC-P - CRYBA1 Antibody (Center) AP12377c
    CRYBA1 Antibody (Center) (Cat. #AP12377c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRYBA1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05813
Other Accession NP_005199.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25150 Da
Antigen Region 104-133 aa
Additional Information
Gene ID 1411
Other Names Beta-crystallin A3, Beta-crystallin A3, isoform A1, Delta4 form, Beta-crystallin A3, isoform A1, Delta7 form, Beta-crystallin A3, isoform A1, Delta8 form, CRYBA1, CRYB1
Target/Specificity This CRYBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the Central region of human CRYBA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRYBA1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CRYB1
Function Crystallins are the dominant structural components of the vertebrate eye lens.
Research Areas
Citations (0)

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Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.


Xu, J., et al. Mol. Vis. 16, 438-444 (2010) :
Gu, Z., et al. Mol. Vis. 16, 154-160 (2010) :
Srivastava, K., et al. Biochemistry 48(30):7179-7189(2009)
Gupta, R., et al. J. Biol. Chem. 284(27):18481-18492(2009)
Takata, T., et al. Mol. Vis. 15, 241-249 (2009) :

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$ 295.00
$ 99.00
Cat# AP12377c
(40 western blots)
Availability: In Stock
Bulk Size
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