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GBRR3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GBRR3 Antibody (N-term) AP12407a
    Anti-GBRR3 Antibody (N-term) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 54 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession A8MPY1
Other Accession NP_001099050.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54272 Da
Antigen Region 35-63 aa
Additional Information
Gene ID 200959
Other Names Gamma-aminobutyric acid receptor subunit rho-3, GABA(A) receptor subunit rho-3, GABA(C) receptor, GABRR3
Target/Specificity This GBRR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human GBRR3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGBRR3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GABRR3
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel (By similarity).

References

Craddock, N., et al. Mol. Psychiatry 15(2):146-153(2010)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
Alakuijala, A., et al. Brain Res. Dev. Brain Res. 154(1):15-23(2005)
Croci, C., et al. J. Biol. Chem. 278(8):6128-6135(2003)

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$ 295.00
$ 99.00
Cat# AP12407a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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