|Application ||WB, E|
|Other Accession||Q9EQS3, Q2TBP7, NP_036465.2|
|Calculated MW||11967 Da|
|Antigen Region||1-30 aa|
|Other Names||C-Myc-binding protein, Associate of Myc 1, AMY-1, MYCBP, AMY1|
|Target/Specificity||This MYCBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYCBP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYCBP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.|
|Cellular Location||Cytoplasm. Nucleus. Mitochondrion. Note=Translocates into the nucleus in the S phase of the cell cycle upon an increase of MYC expression. Found in the mitochondria when associated with AKAP1|
|Tissue Location||Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.
Xiong, J., et al. Oncogene 29(35):4980-4988(2010)
Wang, H.B., et al. J. Gastrointest. Surg. 14(8):1227-1234(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sedoris, K.C., et al. Biochemistry 46(29):8659-8668(2007)
Ishizaki, R., et al. Genes Cells 11(8):949-959(2006)
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