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EIF2B1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - EIF2B1 Antibody (Center) AP12415c
    EIF2B1 Antibody (Center) (Cat. #AP12415c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the EIF2B1 antibody detected the EIF2B1 protein (arrow).
  • IHC-P - EIF2B1 Antibody (Center) AP12415c
    EIF2B1 Antibody (Center) (Cat. #AP12415c)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - EIF2B1 Antibody (Center) AP12415c
    EIF2B1 Antibody (Center) (Cat. #AP12415c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14232
Other Accession Q4R4V8, NP_001405.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33712 Da
Antigen Region 136-163 aa
Additional Information
Gene ID 1967
Other Names Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha, EIF2B1, EIF2BA
Target/Specificity This EIF2B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the Central region of human EIF2B1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEIF2B1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EIF2B1
Synonyms EIF2BA
Function Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Research Areas
Citations (0)

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This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Hiyama, T.B., et al. J. Mol. Biol. 392(4):937-951(2009)
Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
van der Knaap, M.S., et al. Neuropediatrics 38 (5), 264 (2007) :

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$ 295.00
$ 99.00
Cat# AP12415c
(40 western blots)
Availability: In Stock
Bulk Size
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