|Application ||WB, IHC-P, E|
|Other Accession||Q6AXT7, Q91V81, Q0P5L0, NP_077297.2|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||50414 Da|
|Antigen Region||394-422 aa|
|Other Names||RNA-binding protein 42, RNA-binding motif protein 42, RBM42|
|Target/Specificity||This RBM42 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-422 amino acids from the C-terminal region of human RBM42.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RBM42 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.|
|Cellular Location||Nucleus. Cytoplasm. Note=Upon stress response, localizes with HNRNPK in cytoplasmic aggregates of stalled translational preinitiation complexes called stress granules.|
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Provided below are standard protocols that you may find useful for product applications.
RBM42 binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA (By similarity).
Fukuda, T., et al. Genes Cells 14(2):113-128(2009)
Lim, J., et al. Cell 125(4):801-814(2006)
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