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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDC Antibody (Center)   

PDC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PDC Antibody (Center) AP12439c
    PDC Antibody (Center) (Cat. #AP12439c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PDC antibody detected the PDC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20941
Other Accession NP_002588.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28246 Da
Antigen Region 59-88 aa
Additional Information
Gene ID 5132
Other Names Phosducin, PHD, 33 kDa phototransducing protein, Protein MEKA, PDC
Target/Specificity This PDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human PDC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPDC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDC
Function May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX.
Cellular Location Cytoplasm, cytosol. Cell projection, cilium, photoreceptor outer segment Photoreceptor inner segment. Nucleus. Note=Outer and inner segments of the rod cells
Research Areas
Citations (0)

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This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.


Beetz, N., et al. J. Clin. Invest. 119(12):3597-3612(2009)
Klenk, C., et al. J. Biol. Chem. 281(13):8357-8364(2006)
Nishiguchi, K.M., et al. Mol. Vis. 10, 62-64 (2004) :
Margulis, A., et al. Mol. Vis. 8, 477-482 (2002) :
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

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$ 295.00
$ 99.00
Cat# AP12439c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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