|Application ||WB, IHC-P, E|
|Other Accession||NP_001971.2, NP_919337.1|
|Calculated MW||33341 Da|
|Antigen Region||123-152 aa|
|Other Names||Syntaxin-2, Epimorphin, STX2, EPIM, STX2A, STX2B, STX2C|
|Target/Specificity||This STX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-152 amino acids from the Central region of human STX2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EPIM, STX2A, STX2B, STX2C|
|Function||Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.|
|Cellular Location||Membrane; Single-pass type IV membrane protein|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)
Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008)
Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007)
Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005) :
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