|Application ||WB, IHC-P, E|
|Calculated MW||44002 Da|
|Antigen Region||106-135 aa|
|Other Names||Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Protease nexin I, Serpin E2, SERPINE2, PI7, PN1|
|Target/Specificity||This SERPINE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human SERPINE2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SERPINE2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
SERPINE2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Bianchini, G., et al. J. Clin. Oncol. 28(28):4316-4323(2010)
Hersh, C.P., et al. Am. J. Respir. Crit. Care Med. 182(5):605-613(2010)
Hultman, K., et al. J. Neurosci. Res. 88(11):2441-2449(2010)
Kim, W.J., et al. Eur. Respir. J. (2010) In press :
Sorheim, I.C., et al. Clin Respir J 2 SUPPL 1, 129-131 (2008) :
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