|Application ||WB, IHC-P, FC, E|
|Other Accession||P32233, Q3MHP5, NP_004138.1|
|Calculated MW||40542 Da|
|Antigen Region||334-363 aa|
|Other Names||Developmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, DRG1, NEDD3|
|Target/Specificity||This DRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-363 amino acids from the C-terminal region of human DRG1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DRG1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.|
|Cellular Location||Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes|
|Tissue Location||High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
DRG1 may play a role in cell proliferation, differentiation and death.
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Bandyopadhyay, S., et al. Cancer Res. 66(24):11983-11990(2006)
Bandyopadhyay, S., et al. Oncogene 23(33):5675-5681(2004)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Bandyopadhyay, S., et al. Cancer Res. 63(8):1731-1736(2003)
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