|Application ||WB, IHC-P, FC, E|
|Other Accession||P32233, Q3MHP5, NP_004138.1|
|Calculated MW||40542 Da|
|Antigen Region||334-363 aa|
|Other Names||Developmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, DRG1, NEDD3|
|Target/Specificity||This DRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-363 amino acids from the C-terminal region of human DRG1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DRG1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.|
|Cellular Location||Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes|
|Tissue Location||High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
DRG1 may play a role in cell proliferation, differentiation and death.
de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Bandyopadhyay, S., et al. Cancer Res. 66(24):11983-11990(2006)
Bandyopadhyay, S., et al. Oncogene 23(33):5675-5681(2004)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Bandyopadhyay, S., et al. Cancer Res. 63(8):1731-1736(2003)
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