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CLDN2 Antibody (C-term Y195)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLDN2 Antibody (C-term Y195) AP12632b
    Western blot analysis of CLDN2 (arrow) using rabbit polyclonal CLDN2 Antibody (Y195) (Cat. #AP12632b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLDN2 gene.
  • IHC-P - CLDN2 Antibody (C-term Y195) AP12632b
    CLDN2 Antibody (C-term Y195) (Cat. #AP12632b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term Y195) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CLDN2 Antibody (C-term Y195) AP12632b
    CLDN2 Antibody (C-term Y195) (Cat. #AP12632b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57739
Other Accession NP_001164566.1, NP_065117.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24549 Da
Antigen Region 174-201 aa
Additional Information
Gene ID 9075
Other Names Claudin-2, SP82, CLDN2
Target/Specificity This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the C-terminal region of human CLDN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLDN2 Antibody (C-term Y195) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLDN2
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
Cellular Location Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.


Smith, A.J., et al. J. Acquir. Immune Defic. Syndr. 55(3):306-315(2010)
Kojima, F., et al. Oncol. Rep. 23(4):927-931(2010)
Szakal, D.N., et al. Virchows Arch. 456(3):245-250(2010)
Buchert, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2628-2633(2010)
Mankertz, J., et al. Cell Tissue Res. 336(1):67-77(2009)

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$ 295.00
$ 99.00
Cat# AP12632b
(40 western blots)
Availability: In Stock
Bulk Size
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