|Application ||WB, FC, E|
|Calculated MW||52432 Da|
|Antigen Region||221-250 aa|
|Other Names||Cytochrome P450 20A1, 114--, CYP20A1|
|Target/Specificity||This CYP20A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the Central region of human CYP20A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYP20A1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq].
Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
Jiang, J.H., et al. Ai Zheng 23(6):672-677(2004)
Nelson, D.R., et al. Pharmacogenetics 14(1):1-18(2004)
Werck-Reichhart, D., et al. Genome Biol. 1 (6), REVIEWS3003 (2000) :
Smith, G., et al. Xenobiotica 28(12):1129-1165(1998)
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