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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   CTAGE5 Antibody (C-term)   

CTAGE5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CTAGE5 Antibody (C-term) AP12748b
    CTAGE5 Antibody (C-term) (Cat. #AP12748b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CTAGE5 antibody detected the CTAGE5 protein (arrow).
  • IHC-P - CTAGE5 Antibody (C-term) AP12748b
    CTAGE5 Antibody (C-term) (Cat. #AP12748b)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTAGE5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O15320
Other Accession NP_976231.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90996 Da
Antigen Region 775-804 aa
Additional Information
Gene ID 4253
Other Names cTAGE family member 5, Protein cTAGE-5, Meningioma-expressed antigen 6/11, CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Target/Specificity This CTAGE5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 775-804 amino acids from the C-terminal region of human CTAGE5.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCTAGE5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTAGE5 (HGNC:7057)
Function Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Endoplasmic reticulum exit sites
Tissue Location Isoform 5A is expressed only in testis (at the protein level). Other isoforms are expressed in several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B are expressed in cutaneous T- cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A, is expressed in head and neck squamous cell carcinoma
Research Areas
Citations (0)

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Background

CTAGE5 is a tumor-associated antigen.

References

Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Usener, D., et al. J. Invest. Dermatol. 121(1):198-206(2003)
Comtesse, N., et al. Oncogene 21(2):239-247(2002)

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$ 295.00
$ 99.00
Cat# AP12748b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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