|Application ||WB, IHC-P, E|
|Other Accession||P30677, P38408, NP_004288.1|
|Calculated MW||41571 Da|
|Antigen Region||4-33 aa|
|Other Names||Guanine nucleotide-binding protein subunit alpha-14, G alpha-14, G-protein subunit alpha-14, GNA14|
|Target/Specificity||This GNA14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of human GNA14.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNA14 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lee, M.M., et al. J. Leukoc. Biol. 86(6):1319-1329(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
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