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SULF2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SULF2 Antibody (C-term) AP12788b
    Western blot analysis of lysate from MCF-7 cell line, using SULF2 Antibody (C-term)(Cat. #AP12788b). AP12788b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IWU5
Other Accession Q8CFG0, NP_001155313.1, NP_061325.1, NP_940998.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 100455 Da
Antigen Region 824-852 aa
Additional Information
Gene ID 55959
Other Names Extracellular sulfatase Sulf-2, hSulf-2, 316-, SULF2, KIAA1247
Target/Specificity This SULF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 824-852 amino acids from the C-terminal region of human SULF2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSULF2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SULF2
Synonyms KIAA1247
Function Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
Cellular Location Endoplasmic reticulum. Golgi apparatus, Golgi stack. Cell surface Note=Also localized on the cell surface.
Tissue Location Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta
Research Areas
Citations (0)

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Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).


Lai, J.P., et al. Hepatology 52(5):1680-1689(2010) Ellinor, P.T., et al. Nat. Genet. 42(3):240-244(2010) Lemjabbar-Alaoui, H., et al. Oncogene 29(5):635-646(2010) Tang, R., et al. J. Biol. Chem. 284(32):21505-21514(2009) Chau, B.N., et al. Cancer Res. 69(4):1368-1374(2009)

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$ 295.00
$ 99.00
Cat# AP12788b
(40 western blots)
Availability: In Stock
Bulk Size
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