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ABRA Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP12828b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP12828b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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ABRA Antibody (C-term) - Product info | |
| Application | WB, IHC
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| Primary Accession | Q8N0Z2 |
| Other Accession | NP_631905.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 43117 Da |
ABRA Antibody (C-term) - Additional info | |
| Gene ID 137735 | |
| Other Names ABRA; Actin-binding Rho-activating protein; Striated muscle activator of Rho-dependent signaling | |
| Target/Specificity This ABRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-312 amino acids from the C-terminal region of human ABRA. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABRA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABRA Antibody (C-term) - Protein Information | |
| Name ABRA | |
| Function Acts as an activator of serum response factor (SRF)- dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity) | |
| Cellular Location Cytoplasm, myofibril, sarcomere (By similarity). Cytoplasm, cytoskeleton (By similarity) Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines (By similarity) | |
ABRA Antibody (C-term) - Related products
ABRA Antibody (C-term) - Application data
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ABRA Antibody (C-term) (Cat. #AP12828b) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the ABRA antibody detected the ABRA protein (arrow).
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ABRA Antibody (C-term) (Cat. #AP12828b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABRA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ABRA Antibody (C-term) - Research Areas
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BACKGROUND
ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).
REFERENCES
Lamon, S., et al. J. Physiol. (Lond.) 587 (PT 8), 1795-1803 (2009) : Kuwahara, K., et al. J. Clin. Invest. 117(5):1324-1334(2007) Kuwahara, K., et al. Mol. Cell. Biol. 25(8):3173-3181(2005) Arai, A., et al. J. Biol. Chem. 277(27):24453-24459(2002) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
