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CRHBP Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CRHBP Antibody (N-term) AP12892a
    Western blot analysis of CRHBP (arrow) using rabbit polyclonal CRHBP Antibody (N-term) (Cat. #AP12892a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CRHBP gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P24387
Other Accession NP_001873.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36144 Da
Antigen Region 7-36 aa
Additional Information
Gene ID 1393
Other Names Corticotropin-releasing factor-binding protein, CRF-BP, CRF-binding protein, Corticotropin-releasing hormone-binding protein, CRH-BP, CRHBP, CRFBP
Target/Specificity This CRHBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human CRHBP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRHBP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CRFBP
Function Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Cellular Location Secreted.
Research Areas
Citations (0)

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Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Holliday, K.L., et al. J Psychosom Res 68(5):469-474(2010)
Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :

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$ 295.00
$ 99.00
Cat# AP12892a
(40 western blots)
Availability: In Stock
Bulk Size
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