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GCDH Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GCDH Antibody (C-term) AP12905b
    Western blot analysis of GCDH (arrow) using rabbit polyclonal GCDH Antibody (C-term) (Cat. #AP12905b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GCDH gene.
  • IHC-P - GCDH Antibody (C-term) AP12905b
    GCDH Antibody (C-term) (Cat. #AP12905b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GCDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92947
Other Accession Q8HXX8, Q2KHZ9, NP_000150.1, NP_039663.1
Reactivity Human
Predicted Bovine, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48127 Da
Antigen Region 336-365 aa
Additional Information
Gene ID 2639
Other Names Glutaryl-CoA dehydrogenase, mitochondrial, GCD, GCDH
Target/Specificity This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human GCDH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGCDH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.
Cellular Location Mitochondrion matrix.
Tissue Location Isoform 1 and isoform 2 are expressed in fibroblasts and liver
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Park, J.D., et al. J. Korean Med. Sci. 25(6):957-960(2010)
Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)

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$ 295.00
$ 99.00
Cat# AP12905b
(40 western blots)
Availability: In Stock
Bulk Size
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