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KCND1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCND1 Antibody (N-term) AP13021A
    KCND1 Antibody (N-term) (Cat. #AP13021a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the KCND1 antibody detected the KCND1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NSA2
Other Accession Q03719, Q52PG9, NP_004970.3
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 71330 Da
Antigen Region 118-147 aa
Additional Information
Gene ID 3750
Other Names Potassium voltage-gated channel subfamily D member 1, Voltage-gated potassium channel subunit Kv41, KCND1
Target/Specificity This KCND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human KCND1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCND1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCND1
Function Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
Cellular Location Membrane; Multi-pass membrane protein. Cell projection, dendrite
Tissue Location Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus; detected at lower levels in the other parts of the brain.
Research Areas
Citations (0)

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle.


Jang, S.H., et al. Biochem. Biophys. Res. Commun. 384(2):180-186(2009)
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)
Jerng, H.H., et al. Biophys. J. 87(4):2380-2396(2004)
Nakamura, T.Y., et al. FEBS Lett. 499(3):205-209(2001)
Isbrandt, D., et al. Genomics 64(2):144-154(2000)

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$ 295.00
$ 99.00
Cat# AP13021A
(40 western blots)
Availability: In Stock
Bulk Size
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